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Cell Meter™荧光法线粒体过氧化物检测试剂盒*适合于流式细胞仪*

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品牌: AAT Bioquest
型号: 22970
规格: 100 Tests
单价: 3540.00元/
所在地: 天津
有效期至: 长期有效
浏览次数: 1
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产品详细说明
Mitochondria are major producers of cellular superoxide. The production of low to moderate levels of superoxide is critical for the proper regulation of many essential cellular processes including gene expression, signal transduction, and muscle adaptation to endurance exercise training. Uncontrolled mitochondrial superoxide production can trigger cellular oxidative damage that contributes to the pathogenesis of a wide variety of disorders including cancer, cardiovascular diseases, neurodegenerative diseases and aging. Therefore, the detection of intracellular mitochondrial superoxide is of central importance to understanding proper cellular redox regulation and the impact of its dysregulation on various pathologies. Cell Meter™ Fluorimetric Mitochondrial Superoxide Activity Assay Kit uses our unique superoxide indicator to quantify superoxide level in live cells. MitoROS™ 580 is live-cell permeant and can rapidly and selectively target superoxide in mitochondria. It generates red fluorescence when it reacts with superoxide, and can be easily read at Ex/Em = 540/590 nm. The Cell Meter™ Fluorimetric Intracellular Superoxide Detection Kit provides a sensitive, one-step fluorimetric assay to detect mitochondrial superoxide in live cells with one hour incubation. This kit is optimized for flow cytometry applications.

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